The major committees are the Executive Committee (ExCom), the six (6) Sectoral Committees, and an Advisory Committee (AdCom).  Foreign organizations, its branches and affiliates, cannot participate in the selection of PSRs. Organizations having government officials as ex-officio members or which is operating projects from the funds of the government are also disqualified.

The ExCom is composed of one-fourth of the total Council membership to be selected by the Council provided all sectoral committee chairmen shall automatically become members of the Executive Committee. Its officers shall be the Council Chairman, Co-Chairman and Vice-Chairman who shall have the same position in the ExCom. Its major function is to act for and in behalf of the Council when it is not in session. The Council shall provide for its other functions.

The six sectoral committees include:

1. Social Development,
2. Economic Development,
3. Watershed and Environmental Management,
4. Infrastructure Development,
5. Development Administration, and
6.
Indigenous Peoples Concerns.

These sectoral committees shall perform functions analogous to and supportive of the functions of the RDC. They shall review and endorse matters pertaining to their respective sectors in the RDC Executive Committee and / or the RDC Full Council review and endorse national plans, programs and projects proposed for implementation in the regions; 

The current members and officers of the RDC are shown here.

The AdCom is created to further strengthen the coordinative and consultative mechanism in the regions. Composed of the Congressmen from the region and members of the RDC ExCom, it shall advise, assist and support the Council in discharging its functions. Membership of a Congressman is voluntary in the sense that they need to signify in writing their intention to join.

The various committees councils organized to carry out national and agency programs in the region are considered to be under the umbrella of the RDC such as the Regional Project Monitoring Committee (RPMC), the Regional Disaster Coordinating Council (RDCC) and others.  Their role shall be to assist the RDC coordinate, monitor and evaluate their respective specific concerns.

In general, the secretariat functions to these bodies shall be provided by the lead agency that organized the council / committee. The institutional relationship between the RDC and these various committees and councils shall be defined by the council.